Shalin Mehta, Ph.D.
I am Assistant Research Scientist at Marine Biological Laboratory. My interests lie at the intersection of light microscopy, signal processing, and biophysics. I developed quantitative high-resolution phase imaging methods for label-free microscopy during my Ph.D. During my postdoctoral work, supported by Human Frontier Science Program (HFSP), I have developed imaging approaches that reveal molecular alignment of cellular structures by exploiting their interaction with polarization of light. Presence of dynamic aligned structures (such as DNA, membrane, cytoskeleton, extracellular matrix) maintained at the expense of chemical energy distinguishes life from death. I have recently begun to study effects of acute metabolic disruptions on key cellular structures, starting with cytoskeleton. I enjoy thinking about biological processes as spatio-temporal signals that we decipher with help of microscopes and biochemical techniques.