Staff Scientist, University of Chicago & Marine Biological Laboratory
7 MBL Street, L110
Woods Hole, MA 02543
email: shalin.mehta [at] gmail [dot] com
I develop microscopes and computational algorithms to visualize invisible biological processes. My current work focuses on imaging molecular order in living systems at scales ranging from single molecules to sub-cellular assemblies to tissues.
During my PhD with Colin Sheppard at National University of Singapore, I developed models and microscopes for high-resolution imaging of live cells without an external label. First as an HFSP postdoctoral fellow with Rudolf Oldenbourg and Tomomi Tani, and later as Assistant Research Scientist at Marine Biological Laboratory, Woods Hole, I have developed new imaging and computational methods that reveal molecular order in living systems. We exploit a property of light not visible to human eye, but as fundamental as color and brightness, called polarization, to measure molecular order below the resolution limit of the microscope. In my current role as Staff Scientist with Patrick La Riviere at University of Chicago and Marine Biological Laboratory, I integrate approaches from optics, computation, and biology to study emergence of molecular order in three-dimensional cells and tissues.